Sant\u00e9 Canada a r\u00e9cemment approuv\u00e9 une nouvelle th\u00e9rapie modificatrice de la maladie (DMT) pour le traitement des patients atteints de la maladie d’Alzheimer (MA) pr\u00e9coce. Cela marque un tournant passionnant dans les soins de la MA, le Canada rejoignant d’autres pays en adoptant ce traitement innovant pour lutter contre la MA. \u00c0 mesure que les premiers DMT entrent en pratique clinique canadienne, les radiologistes joueront un r\u00f4le crucial pour assurer une prestation de traitement s\u00fbre, pr\u00e9cise et efficace.<\/p>\n\n\n\n
Lecanemab (LEQEMBI\u00ae), un traitement anti-amylo\u00efde, est indiqu\u00e9 pour les personnes vivant aux premiers stades de la maladie (d\u00e9finie comme un trouble cognitif l\u00e9ger ou une d\u00e9mence l\u00e9g\u00e8re). Les sp\u00e9cialistes de la maladie d’alzheimer auront besoin du soutien de la radiologie pour s\u00e9lectionner les patients appropri\u00e9s \u00e0 recevoir en utilisant des protocoles sp\u00e9cifiques de d\u00e9mence cognitive pour le d\u00e9pistage.<\/p>\n\n\n\n
Au-del\u00e0 du diagnostic, la neuroimagerie joue un r\u00f4le crucial dans la surveillance des patients une fois le traitement initi\u00e9. Les th\u00e9rapies anti-amylo\u00efdes, comme le lecanemab, sont associ\u00e9es \u00e0 des anomalies d’imagerie li\u00e9es \u00e0 l’amylo\u00efde (ARIA), qui peuvent se manifester sous deux formes : ARIA avec \u0153d\u00e8me\/\u00e9panchement (ARIA-E) ou ARIA avec h\u00e9mosid\u00e9rine\/h\u00e9morragie (ARIA-H). Bien que les ARIA soient souvent asymptomatiques, la d\u00e9tection pr\u00e9coce est essentielle pour \u00e9clairer les d\u00e9cisions de traitement et minimiser le risque global pour le patient. Le taux d’\u00e9v\u00e9nements d’ARIA est sp\u00e9cifique \u00e0 chaque m\u00e9dicament anti-amylo\u00efde et peut varier selon les traitements.<\/p>\n\n\n\n
Les protocoles de surveillance actuels pr\u00e9voient qu’une IRM de r\u00e9f\u00e9rence soit r\u00e9alis\u00e9e avant le d\u00e9but du traitement ainsi que des examens fr\u00e9quents \u00e0 intervalles d\u00e9finis tout au long du traitement. Pour tous les d\u00e9tails sur les protocoles de surveillance IRM, consultez la monographie canadienne de produits LEQEMBI\u00ae<\/a> et les programmes \u00e9ducatifs disponibles sur www.understandingARIA.ca<\/a><\/p>\n\n\n\n Les responsabilit\u00e9s du radiologue de d\u00e9tecter les changements subtils d’imagerie, de distinguer l’ARIA des autres pathologies et de communiquer efficacement avec le m\u00e9decin traitant les placent au premier plan des soins aux patients. L’expertise en radiologie sera essentielle pour soutenir la prise de d\u00e9cision multidisciplinaire.<\/p>\n\n\n\n L’approbation du lecanemab marque bien plus que l’arriv\u00e9e d’une nouvelle option th\u00e9rapeutique dans la DA. Cela signale un virage vers des soins de la MA, ax\u00e9s sur les biomarqueurs et intensives en imagerie, o\u00f9 une approche multidisciplinaire devient encore plus importante. Cette avanc\u00e9e annonce aussi un nouvel espoir pour les patients atteints de la DA et pour leurs aidants.<\/p>\n\n\n\n \u00c0 cette nouvelle \u00e8re o\u00f9 l’imagerie guidera le diagnostic, prot\u00e9gera et \u00e9clairera les d\u00e9cisions th\u00e9rapeutiques, la communaut\u00e9 radiologique devient une force centrale dans l’\u00e9laboration des r\u00e9sultats des patients. Leur expertise garantit qu’\u00e0 mesure que l’innovation s’acc\u00e9l\u00e8re, la s\u00e9curit\u00e9 des patients demeure au c\u0153ur des soins de la DA.<\/p>\n","protected":false},"excerpt":{"rendered":" Sant\u00e9 Canada a r\u00e9cemment approuv\u00e9 une nouvelle th\u00e9rapie modificatrice de la maladie (DMT) pour le traitement des patients atteints de la maladie d’Alzheimer (MA) pr\u00e9coce. Cela marque un tournant passionnant dans les soins de la MA, le Canada rejoignant d’autres pays en adoptant ce traitement innovant pour lutter contre la MA. \u00c0 mesure que les 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Cela marque un tournant passionnant dans les soins de la MA, le Canada rejoignant d’autres pays en adoptant ce traitement innovant pour lutter contre la MA. \u00c0 mesure que les\u2026","_links":{"self":[{"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/posts\/18251","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/comments?post=18251"}],"version-history":[{"count":2,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/posts\/18251\/revisions"}],"predecessor-version":[{"id":18340,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/posts\/18251\/revisions\/18340"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/media\/18249"}],"wp:attachment":[{"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/media?parent=18251"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/categories?post=18251"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/tags?post=18251"},{"taxonomy":"post_topic_taxonomy","embeddable":true,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/post_topic_taxonomy?post=18251"},{"taxonomy":"post_modality_taxonomy","embeddable":true,"href":"https:\/\/car.ca\/fr\/wp-json\/wp\/v2\/post_modality_taxonomy?post=18251"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}